EPHA6 Kinase Assay Service

Activity-based EPHA6 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
EPHA6

Enzyme
Human EPHA6

HGNC
EPHA6

Synonym
EHK2, EHK-2, EPA6

Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 29
PP2 140
AG1478 225
PDGFR I-III >100,000
D-64406 15,500
Scientific Information
Q9UF33 (http://www.uniprot.org/uniprot/Q9UF33)

Screening Location
Malvern, USA

Reference compound IC50 for EPHA6
Reference compound IC50 for EPHA6

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