HDAC10 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
HDAC10
Enzyme
Human HDAC10
Synonyms
Polyamine deacetylase HDAC10, Class II
Substrates
Ac-Spermidine-AMC, 12.5 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Quisinostat | 3.62 |
| Trichostatin A | 59.5 |
| TMP269 | 50,400 |
| Vorinostat | 198 |
Scientific Information
Q969S8 (https://www.uniprot.org/uniprotkb/Q969S8)
Screening Location
Malvern, PA, USA
Further information
More information can be found on our website HDAC Assay (Histone Deacetylase Assay) and Sirtuin Assay Services.
Reference Compound IC50 for HDAC10
