HDAC11 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
HDAC11
Enzyme
Human HDAC11
Synonyms
Histone deacetylase 11, HD11, HDA11
Scientific Information
Q96DB2 (http://www.uniprot.org/uniprot/Q96DB2)
Assay Properties
Substrates
Fluorogenic HDAC Class2a Substrate (Boc-Lys(trifluoroacetyl)-AMC), 50 μM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 2,100 |
| SAHA | >10,000 |
| Panobinostat | 530 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Histone Deacetylase (HDAC) Assay Services
Reference Compound IC50 for HDAC11
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