HDAC2 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
HDAC2
Enzyme
Human HDAC2
Synonyms
Histone Deacetylase 2, Class I
Substrates
Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 10 μM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 8.41 |
| SAHA | 20.3 |
| Panobinostat | 4.53 |
Scientific Information
Q92769 (http://www.uniprot.org/uniprot/Q92769)
Screening Location
Malvern, USA
Further information
More information can be found on our website HDAC Assay (Histone Deacetylase Assay) and Sirtuin Assay Services.
Reference Compound IC50 for HDAC2
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