HDAC3/NCOR2 Assay Services

HDAC3/NCOR2 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
CAT#

HDAC3/NCOR2

Enzyme

Human HDAC3/NCOR2

Synonyms

Histone Deacetylase 3, Class I NCOR2: Nuclear receptor corepressor 2, CTG repeat protein 26, SMAP270

Substrates

Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 10 μM

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Trichostatin A 5.16
SAHA 64.3
Panobinostat 1.12
Scientific Information

HDAC3: O15379 (http://www.uniprot.org/uniprot/O15379)NCOR2: Q9Y618 (http://www.uniprot.org/uniprot/Q9Y618)

Screening Location

Malvern, USA

Further information

More information can be found on our website HDAC Assay (Histone Deacetylase Assay) and Sirtuin Assay Services.

Reference Compound IC50 for HDAC3

Reference Compound IC50 for HDAC3