HDAC4 Assay Services

HDAC4 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.

Target Overview

CAT#

HDAC4

Enzyme

Human HDAC4

Synonyms

Histone Deacetylase 4, Class IIa

Substrates

Fluorogenic HDAC Class2a Substrate (Boc-Lys(trifluoroacetyl)-AMC), 50 μM

Assay Properties

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Trichostatin A 7,300
SAHA 76,000
TMP269 180

Scientific Information

P56524 (http://www.uniprot.org/uniprot/P56524)

Screening Location

Malvern, USA

Reference Compound IC50 for HDAC4

Reference Compound IC50 for HDAC4