HDAC4 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
CAT#
HDAC4
Enzyme
Human HDAC4
Synonyms
Histone Deacetylase 4, Class IIa
Substrates
Fluorogenic HDAC Class2a Substrate (Boc-Lys(trifluoroacetyl)-AMC),
50 μM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 7,300 |
| SAHA | 76,000 |
| TMP269 | 180 |
Scientific Information
P56524 (http://www.uniprot.org/uniprot/P56524)
Screening Location
Malvern, USA
Reference Compound IC50 for HDAC4
