HDAC9 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
HDAC9
Enzyme
Human HDAC9
Synonyms
Histone deacetylase 9, MEF2-interacting transcription repressor MITR, HDAC7B, Class IIa
Substrates
Fluorogenic HDAC Class2a Substrate (Boc-Lys(trifluoroacetyl)-AMC), 50 μM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 7,500 |
| SAHA | 141,000 |
| TMP269 | 21 |
Scientific Information
Q9UKV0 (http://www.uniprot.org/uniprot/Q9UKV0)
Screening Location
Malvern, USA
Reference Compound IC50 for HDAC9
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