IGF1R Kinase Assay Service

Activity-based IGF1R kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
IGF1R

Enzyme
Human IGF1R

HGNC
IGF1R

Synonym
JTK13

Substrates
Peptide substrate, [KKKSPGEYVNIEFG], 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 9.0
PP2 >20,000
Scientific Information
P08069 (http://www.uniprot.org/uniprot/P08069)

Screening Location
Malvern, USA

Reference compound IC50 for IGF1R
Reference compound IC50 for IGF1R

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