Kallikrein 11 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Kallikrein 11
Enzyme
Human Kallikrein 11
Species
Human
Synonym
KLK11, PRSS20, TLSP,hK11, Hippostasin
Scientific Information
Q9UBX7 (https://www.uniprot.org/uniprotkb/Q9UBX7)
Assay Properties
Substrate
Fluorogenic peptide H-D-CHA-Ala-Arg-AMC, 50 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| Gabexate Mesylate | 0.68 |
| Leupeptin | 52.7 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound inhibition of Kallikrein 11
PDF