Kallikrein 3/PSA Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Kallikrein 3/PSA
Enzyme
Human Kallikrein 3
Species
Human
Synonym
Prostate-specific antigen, PSA, KLK3, APS, Gamma-seminoprotein (Seminin), P-30 antigen, Semenogelase
Scientific Information
P07288 (https://www.uniprot.org/uniprotkb/P07288)
Assay Properties
Substrate
Fluorogenic peptide Mu-HSSKLQ-AMC, 50 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| Gabexate Mesylate | >100 |
| Leupeptin | >100 |
| Camostat Mesylate | >100 |
| Nafamostat Mesylate | >100 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound inhibition of Kallikrein 3/PSA
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