Kallikrein 4 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Kallikrein 4
Enzyme
Human Kallikrein 4
Species
Human
Synonym
KLK4, EMSP1, PRSS17, PSTS, Prostase
Scientific Information
Q9Y5K2 (https://www.uniprot.org/uniprotkb/Q9Y5K2)
Assay Properties
Substrate
Fluorogenic peptide Boc-Val-Pro-Arg-AMC, 10 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Gabexate Mesylate | 38 |
| Leupeptin | 235 |
| Camostat Mesylate | 2.5 |
| Nafamostat Mesylate | 0.33 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound inhibition of Kallikrein 4
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