Kallikrein 6 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Kallikrein 6
Enzyme
Human Kallikrein 6
Species
Human
Synonym
KLK6, PRSS18, PRSS9, SP59, Protease M, Neurosin, Zyme
Scientific Information
Q92876 (https://www.uniprot.org/uniprotkb/Q92876)
Assay Properties
Substrate
Fluorogenic peptide Boc-Gln-Ala-Arg-AMC, 5 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| Gabexate Mesylate | 3.8 |
| Leupeptin | 8 |
| Camostat Mesylate | 0.17 |
| Nafamostat Mesylate | 0.36 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound inhibition of Kallikrein 6
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