Kallikrein 8 Protease Assay Service

Kallikrein 8 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.

Target Overview
CAT#

Kallikrein 8

Enzyme

Human Kallikrein 8

Species

Human

Synonym

KLK8, NRPN, PRSS19, TADG14, Neuropsin (NP), Ovasin, hK8

Scientific Information

O60259 (https://www.uniprot.org/uniprotkb/O60259)

Assay Properties
Substrate

Fluorogenic peptide Boc-Val-Pro-Arg-AMC, 10 µM

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Gabexate Mesylate 44
Leupeptin 102
Camostat Mesylate 4.2
Nafamostat Mesylate 1.8
Screening Location

Malvern, PA, USA

Further Information

More information can be found on our website Protease Assay Services

Reference compound inhibition of Kallikrein 8

Reference compound inhibition of Kallikrein 8