Activity-based KIF20A (MKLP2) Kinesin ATPase assay for compound screening and profiling via ADP-Glo™.
Target Overview
CAT#
KIF20A
Enzyme
Human KIF20A (1-519aa)
Family
Kinesin-6
Synonym
MKLP2, RAB6KIFL, GG10_2, Rabkinesin-6, Rab6-interacting kinesin-like protein
Scientific Information
O95235 (http://www.uniprot.org/uniprot/O95235)
Assay Properties
Substrates
Tubulin Microtubules, 0.1 mg/ml
ATP, 10 µM
ATP, 10 µM
Reaction
ATP = ADP + Pi
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Paprotrain | 232 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinesin ATPase Assay Services
Reference compound IC50 for KIF20A
PDF