Lymphocyte-specific protein-tyrosine kinase (Lck) activity-based Assay for compound screening and profiling via ADP-Glo kinase assay.
Target Overview
CAT#
Lck
GPCR Target
Human Lck
Source
His-tagged recombinant protein expressed in insect cells
Scientific Information
Lck (https://www.uniprot.org/uniprotkb/A0A0S2Z3Y8/entry)
Assay Properties
Protocol
Detection of ATP depletion using the ADP-Glo kinase assay; luminescence measurement
Readout
Luminescence (RLU)
Reference Compound IC50
| Compound IC50 (nM) |
|---|
| Staurosporine (3.3) |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website In Vitro Safety Pharmacology Profiling
Reference compound activity for Lck
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