MAO-A Biochemical Activity Assay Service

Monoamine Oxidase A (MAO-A) activity-based Assay for compound screening and profiling.

Target Overview
CAT#

MAO-A

GPCR Target

Human MAO-A

Source

Recombinant protein expressed in baculovirus infected BTI insect cells

Scientific Information

MAOA (https://www.uniprot.org/uniprotkb/Q49A63/entry)

Assay Properties
Protocol
Detection of Monoamine oxidase activity using Amplex Red; fluorescence measurement
Readout

Fluorescence

Reference Compound IC50
Compound IC50 (nM)
Tranylcypromine (179)
Screening Location

Malvern, PA, USA

Further Information

More information can be found on our website In Vitro Safety Pharmacology Profiling

Reference compound activity for MAO-A

Reference compound binding data for MAO-A