Matriptase/ST14 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Matripase
Enzyme
Human Matripase
Species
Human
Synonym
ST14, PRSS14, SNC19, TADG15, MT-SP1, Suppressor of tumorigenicity 14 protein, Prostamin, Serine protease 14
Scientific Information
Q9Y5Y6 (https://www.uniprot.org/uniprotkb/Q9Y5Y6)
Assay Properties
Substrate
Fluorogenic peptide Boc-Gln-Ala-Arg-AMC, 10 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compound | IC50 (nM) |
|---|---|
| Camostat Mesylate | 1.5 |
| Gabexate Mesylate | 4194 |
| E-64 | >100,000 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assays.
Reference compound inhibition of Matriptase/ST14
