MST2/STK3 Kinase Assay Service

Activity-based MST2/STK3 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
MST2/STK3

Enzyme
Human MST2/STK3

HGNC
STK3

Synonym
MST2, KRS1

Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 9.0
Ro 31-8220 110
GW 5074 560
H-89 19,000
Scientific Information
Q13188 (http://www.uniprot.org/uniprot/Q13188)

Screening Location
Malvern, USA

Reference compound IC50 for MST2/STK3
Reference compound IC50 for MST2/STK3

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