Neprilysin Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Neprilysin
Enzyme
Human Neprilysin
Synonym
Atriopeptidase, Neutral endopeptidase, Skin fibroblast elastase, CALLA, MME, EPN
Substrates
10 µM Fluorogenic peptide MCA-RPPGFSAFK(Dnp)-OH
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Phosphoramidon | 453 |
Scientific Information
P08473 (https://www.uniprot.org/uniprotkb/P08473/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound IC50 for Neprilysin
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