Nuclear Extract Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Nuclear Extract
Enzyme
Nuclear Extract from HeLa cells
Synonyms
Nuclear Extract of Histone deacetylases
Substrates
Fluorogenic peptide (KAc), 50 μM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 1.20 |
| SAHA | 73.9 |
Screening Location
Malvern, USA
Reference Compound IC50 for Nuclear Extract
PDF