Surface Plasmon Resonance (SPR) technique for evaluating direct binding of small molecule inhibitors to PARG (full-length)
Target Overview
Target
Poly(ADP-ribose) glycohydrolase
HGNC symbol
PARG
Synonyms
hPARG111
Scientific information
PARG: Q86W56 (https://www.uniprot.org/uniprot/Q86W56)
Protein source
Produced at Reaction Biology (AA 1-976)
Screening location
Malvern, PA, USA
Further information
More information can be found on our website SPR Assay Services for Drug Discovery
Binding of PARG inhibitor PDD00017273 to full-length PARG
The data was collected on a Biacore 8K using single-cycle kinetics. The data was analyzed using a 1:1 kinetic binding model.
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