Activity-based PI3KC2B lipid kinase assay for compound screening and profiling via ADP-GloTM kinase assay.
Target Overview
CAT#
PI3KC2B
Enzyme
Human PI3KC2B
HGNC
PI3KC2B
Synonym
P3C2B, PIK3C2B, C2-PI3K
Scientific Information
O00750 (https://www.uniprot.org/uniprotkb/O00750)
Assay Properties
Substrates
PI:PS, 10 µM
ATP, 10 µM
Reaction
1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| PI-103 | 37 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinase Assays
Reference compound IC50 for PI3KC2B
