Activity-based PIK3C2A kinase assay for compound screening and profiling via ADP-Glo – assay technology
Target Overview
RBE Target ID
PIK3C2A
Enzyme
Human PIK3C2A, wt
HGNC
PIK3C2A
Manning ID
N/A
Synonym
CPK, DKFZp686L193, MGC142218, PI3-K-C2(ALPHA), PI3-K-C2A, PI3K-C2alpha, PI3K-C2-alpha, PIK3C2A, PI3-K-C2A, PI3KC2a
UniProt
O00443 (P3C2A_HUMAN)
Kinase Type
Lipid kinase
Kinase Group
PI3K
Assay Properties
Assay Format
ADP-Glo
Substrates
PI, ATP
Reaction
PI + ATP = P-PI + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Wortmannin | 120 |
| LY294002 | 21000 |
| PI-103 | 940 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | PIK3C2A |
| 355 wt Profiler | No |
| 355 IC50 wt Profiler | No |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | Yes |
| IC50 Profiler | IC50 Lipid Kinase Profiler |
Recombinant Protein Availability
| Active recombinant protein | No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
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