Activity-based PIK3C2B kinase assay for compound screening and profiling via ADP-Glo – assay technology
Target Overview
RBE Target ID
PIK3C2B
Enzyme
Human PIK3C2B, wt
HGNC
PIK3C2B
Manning ID
N/A
Synonym
C2-PI3K, DKFZp686G16234, PI3K-C2beta, PI3K-C2-beta, PIK3C2B
UniProt
O00750 (P3C2B_HUMAN)
Kinase Type
Lipid kinase
Kinase Group
PI3K
Assay Properties
Assay Format
ADP-Glo
Substrates
PI:PS, ATP
Reaction
PI:PS + ATP = P-PI:PS + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Wortmannin | 1500 |
| LY294002 | 5200 |
| PI-103 | 15000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | PIK3C2B |
| 355 wt Profiler | No |
| 355 IC50 wt Profiler | No |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | Yes |
| IC50 Profiler | IC50 Lipid Kinase Profiler |
Recombinant Protein Availability
| Active recombinant protein | No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
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