PIP5K1C
Target Overview
RBE Target ID
PIP5K1C
Enzyme
Human PIP5K1C, wt
HGNC
PIP5K1C
Manning ID
N/A
Synonym
LCCS3, PIP5K1-gamma, PIP5Kgamma, PIP5KIgamma, PIPKIg_v4, PtdIns(4)P-5-kinase 1 gamma, PIP5K1C, PIP5K1-gamma, PIP5Kgamma, PIP5K-GAMMA, PIPKIg_v4
UniProt
O60331 (PI51C_HUMAN)
Kinase Type
Lipid kinase
Kinase Group
PIP5K
Assay Properties
Assay Format
ADP-Glo
Substrates
PI:PS, ATP
Reaction
PI:PS + ATP = P-PI:PS + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Wortmannin | 100000 |
| LY294002 | 100000 |
| PI-103 | 100000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | PIP5K1C |
| 355 wt Profiler | No |
| 355 IC50 wt Profiler | No |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | Yes |
| IC50 Profiler | IC50 Lipid Kinase Profiler |
Recombinant Protein Availability
| Active recombinant protein | Yes; ProQinaseTM – PIP5K1C (Activity verified by ADP-Glo – Assay) |
| Product Number | 1222-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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