Surface Plasmon Resonance (SPR) technique for evaluating direct binding of small molecule inhibitors to the SET domain of SETD2
Target Overview
Target
Histone-lysine N-methyltransferase SETD2
HGNC symbol
SETD2
Synonyms
SET2
Scientific information
Q9BYW2 (https://www.uniprot.org/uniprot/Q9BYW2)
Protein source
Produced at Reaction Biology
Screening location
Malvern, PA, USA
Further information
More information can be found on our website SPR Assay Services for Drug Discovery
Binding affinity of SAH for the SET domain of SETD2
The data was collected on a Biacore 8K using multi-cycle kinetics. The data was analyzed using a steady state affinity model.
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