SIRT1 Sirtuin Assay Services

SIRT1 Sirtuin Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
CAT#
SIRT1
Enzyme
Human SIRT1 (NAD+-dependent enzyme)
Synonyms
Sirtuin 1, protein-lysyl-deacetylase, Class III HDAC)
Substrates
Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 50 μM
NAD+, 500 μM
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (μM)
Suramin sodium2.42
ResveratrolActivator
Scientific Information
Q96EB6 (http://www.uniprot.org/uniprot/Q96EB6)
Screening Location
Malvern, USA
Reference Compound IC50 for SIRT1
Reference Compound IC50 for SIRT1
SIRT1 Figure 1