SIRT3 Sirtuin Assay Services

SIRT3 Sirtuin Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
CAT#
SIRT3
Enzyme
Human SIRT3 (NAD+-dependent enzyme)
Synonyms
NAD-dependent deacetylase sirtuin-3, mitochondrial, SIR2-like protein 3, SIR2L3, Class III HDAC)
Substrates
Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 50 μM
NAD+, 500 μM
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (μM)
Nicotinamide35.1
Scientific Information
Q9NTG7 (http://www.uniprot.org/uniprot/Q9NTG7)
Screening Location
Malvern, USA
Reference Compound IC50 for SIRT3
Reference Compound IC50 for SIRT3