Activity-based SLK kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
SLK
Enzyme
Human SLK, wt
HGNC
SLK
Manning ID
SLK
Synonym
KIAA0204, STK2, bA16H23.1, se20-9, STK2, SLK, SLK/STK2
UniProt
Q9H2G2 (SLK_HUMAN)
Kinase Type
Protein kinase
Kinase Group
STE
Assay Properties
Assay Format
33PanQinaseTM
Substrates
RB-S6P, ATP
Reaction
RB-S6P + 33P-ATP = 33P-RB-S6P + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 6 |
| Sorafenib | 8100 |
| Sunitinib | 270 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | SLK |
| 355 wt Profiler | Yes |
| 355 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
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