Activity-based SRPK1 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
SRPK1
Enzyme
Human SRPK1, wt
HGNC
SRPK1
Manning ID
SRPK1
Synonym
SFRSK1, SRPK1
UniProt
Q96SB4 (SRPK1_HUMAN)
Kinase Type
Protein kinase
Kinase Group
CMGC
Assay Properties
Assay Format
33PanQinaseTM
Substrates
MBP, ATP
Reaction
MBP + 33P-ATP = 33P-MBP + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 2300 |
| Sorafenib | 10000 |
| Sunitinib | 100000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | SRPK1 |
| 355 wt Profiler | Yes |
| 355 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | Yes; ProQinaseTM – SRPK1 (Activity verified by 33PanQinaseTM-Assay) |
| Product Number | 0434-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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