Activity-based STK39 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
STK39
Enzyme
Human STK39, wt
HGNC
STK39
Manning ID
STLK3
Synonym
DCHT, SPAK, STLK3, STK39, STK39/STLK3
UniProt
Q9UEW8 (STK39_HUMAN)
Kinase Type
Protein kinase
Kinase Group
STE
Assay Properties
Assay Format
33PanQinaseTM
Substrates
RBER-CDC25tide, ATP
Reaction
RBER-CDC25tide + 33P-ATP = 33P-RBER-CDC25tide + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| JNK-IN-7 | 3915 |
| Sorafenib | 10000 |
| Sunitinib | 62000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | STK39 |
| 355 wt Profiler | Yes |
| 355 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
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