Activity-based TRKA-TPR kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
TRKA, TPR-
Enzyme
Human TPR-TRKA fusion
HGNC
NTRK1-TPR
Synonym
TRKA
Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Screening Location
Malvern, USA
Reference compound IC50 for TRKA-TPR
![](https://www.reactionbiology.com/wp-content/uploads/2023/12/TRKA-TPR_Kin_Malvern.png)