TSSK3/STK22C Kinase Assay Service

Activity-based TSSK3/STK22C kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

TSSK3/STK22C

Enzyme

Human TSSK3/STK22C

HGNC

TSSK3

Synonym

STK22C, STK22D, SPOGA3

Substrates

Peptide substrate, [KKKVSRSGLYRSPSMPENLNRPR], 20 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

Q96PN8 (http://www.uniprot.org/uniprot/Q96PN8)

Screening Location

Malvern, USA

Reference compound IC50 for TSSK3/STK22C