TXK Kinase Assay Service - Reaction Biology

Activity-based TXK kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

TXK

Enzyme

Human TXK

HGNC

TXK

Synonym

BTKL, PSCTK5, PTK4, RLK

Substrates

Peptide substrate, [EAIYAAPFAKKK], 20 µM
ATP, 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

P42681 (http://www.uniprot.org/uniprot/P42681)

Screening Location

Malvern, USA

Reference compound IC50 for TXK