Activity-based ULK2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
ULK2
Enzyme
Human ULK2, wt
HGNC
ULK2
Manning ID
ULK2
Synonym
KIAA0623, Unc51.2, ULK2, ATG1B
UniProt
Q8IYT8 (ULK2_HUMAN)
Kinase Type
Protein kinase
Kinase Group
Other
Assay Properties
Assay Format
33PanQinaseTM
Substrates
Casein, ATP
Reaction
Casein + 33P-ATP = 33P-Casein + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 11 |
| Sorafenib | 10000 |
| Sunitinib | 1900 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | ULK2 |
| 355 wt Profiler | Yes |
| 355 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | Yes; ProQinaseTM – ULK2 (Activity verified by 33PanQinaseTM-Assay) |
| Product Number | 1670-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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