PROTAC mediated ternary complex formation between VHL trimer and target protein.
Target Overview
CAT#
VHL-ternary
Enzyme
VHL/ELOB/ELOC
Scientific Information
Assay Properties
Reaction
VHL-ELOB-ELOC + PROTAC + Target = Ternary Complex
Readout
HTRF
Reference Compound IC50s
MZ1 for selected bromodomain; otherwise target specific
Screening Location
Malvern, PA, USA
Further information
More information can be found on our website Protein Degradation Assay – PROTAC Screening
Reference compound example for VHL
PDF