XIAP Apoptosis Assay for compound screening and profiling using fluorescence polarization to measure compound binding to the target.
Target Overview
CAT#
XIAP
Enzyme
Human XIAP BIR3 domain
Synonyms
E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 4, IAP-like protein, Inhibitor of apoptosis protein 3, RING-type E3 ubiquitin transferase XIAP, IAP3, BIRC4
Substrates
Fluorescence-labeled Probe, 5 nM
Assay Properties
Reaction
Competition binding assay with probe in FP assay.
Reference Compound IC50s
Scientific Information
P98170 (http://www.uniprot.org/uniprot/P98170)
Screening Location
Malvern, USA
Probe displacement IC50 for XIAP
