YES/YES1 Kinase Assay Service

Activity-based YES/YES1 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
YES/YES1

Enzyme
Human YES/YES1

HGNC
YES1

Synonym
C-YES, HsT441, P61-YES, YES1

Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Scientific Information
P07947 (http://www.uniprot.org/uniprot/P07947)

Screening Location
Malvern, USA

Reference compound IC50 for YES/YES1

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