YSK4/MAP3K19 Kinase Assay Service

Activity-based YSK4/MAP3K19 kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

YSK4/MAP3K19

Enzyme

Human YSK4/MAP3K19

HGNC

MAP3K19

Synonym

M3K19, RCK, YSK4

Substrates

MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

Q56UN5 (http://www.uniprot.org/uniprot/Q56UN5)

Screening Location

Malvern, USA

Reference compound IC50 for YSK4/MAP3K19