ZAK/MLTK Kinase Assay Service

Activity-based ZAK/MLTK kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

ZAK/MLTK

Enzyme

Human ZAK/MLTK

HGNC

MAP3K20

Synonym

MLTK, mlklak, ZAK

Substrates

MBP (Myelin Basic Protein), 10 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

Q9NYL2 (http://www.uniprot.org/uniprot/Q9NYL2)

Screening Location

Malvern, USA

Reference compound IC50 for ZAK/MLTK