List of Targets
Target | HGNC symbol | Synonyms | Data |
---|---|---|---|
AR | AR | Androgen receptor, AIS, NR3C4, SMAX1, HUMARA | Data sheet |
FXR | NR1H4 | Farnesoid X receptor, RIP14, HRR1, HRR-1 | Please inquire |
PXR | NR1I2 | Pregnane X receptor, steroid and xenobiotic sensing nuclear receptor (SXR) | Data sheet |
Further nuclear receptor assays can be setup immediately upon request. Please inquire.
Assay Details
Setups: IC50 value determination in an 8-dose duplicate assay format. Free choice for screening of the kinase targets of your choice. New target development/validation is available upon request.
Controls: We use DMSO as a negative control. In every project, testing of a standard reference compound is included in IC50 assay format as well.
Turnaround time: We strive to complete your project within 2-3 weeks. Expedited scheduling and data delivery can be arranged prior to study commencement.
Report: A detailed report including assay conditions and comprehensive evaluation of data as well as raw data for each analysis will be provided.
Screening location: Malvern, PA, USA
Compound requirements: In brief, 50 to 100 µl of a 10 to 50 mM DMSO stock or 2-3 mg solid material is needed. Please refer to our FAQs for information regarding compound preparation and shipping.