This convenient service screens your compounds against over 100 targets known to be involved in human toxicity to aid with compound selection and early safety assessments. Available assay formats include enzymatic, biochemical binding, cell-based functional, and radioligand binding assays.
The cardiac safety assessment assays are available for preclinical evaluation of the safety of compounds to identify toxic drugs potentially inducing fatal cardiac tachyarrhythmia.
The identification of the Maximum-Tolerated Dose (MTD) is one of the first steps when taking a drug candidate from in vitro to in vivo phase of drug discovery. The MTD is the dose at which certain toxicity specified in advance occurs only in a predetermined tolerable proportion of the animals.
