Hollow Fibers: A Bridge to Preclinical Success

Hollow Fibers: A Bridge to Preclinical Success

In the early 1990s, the discovery of promising anti-cancer agents from large-scale 60-cell line screens created an overwhelming demand for testing in traditional xenograft models. The sheer number of compounds needing evaluation far exceeded the resources available....
Spotlight: Activity-Based Kinase Assay Formats

Spotlight: Activity-Based Kinase Assay Formats

Reaction Biology’s Assay Formats HotSpot™ Kinase Screen Using the Gold Standard Radiometric Assay The HotSpot™ Kinase Screen uses a radiometric assay format, which directly measures kinase activity by detecting the incorporation of radioactive phosphate into the...
SubQperior™: Why Superior?

SubQperior™: Why Superior?

Testing the efficacy of lead compounds in animal models is a crucial step in preclinical drug development. Researchers have many in vivo tumor models to choose from, but selecting the right one involves considering factors such as cost, time, and technical expertise....